At the heart of QIAGEN’s business is a vision to make improvements in life possible.
We are on an exciting mission to make a real difference in science and healthcare. We are still the entrepreneurial company we started out as and have today achieved a size where we can bring our full power to many initiatives and to our presence across the globe.The Associate Principal Scientist will join the PCR and Enzymes R&D team and have a leadership role, responsible for design, engineering, expression, and purification of enzymes and proteins with applications in life sciences and diagnostics fields. The ideal candidate will have experience in protein engineering, directed evolution, and be familiar with high-throughput enzyme engineering technologies. An expertise in designing expression DNA constructs.
Strong experience in protein expression and purification processes is critical. The person will be working in a cross-functional team and required to support both internal and external (customer defined) projects. This position requires a deep understanding of protein chemistry, molecular biology, and biopharmaceutical development processes
Responsibilities:
- Design, construct, express, and perform screening/selection assays for recombinant proteins.
- Participate in protein expression optimization and purification at different scales.
- Design and implement assays for enzyme characterization.
- Use and direct a range of methods for protein engineering including: rational design, structure analysis, directed evolution as well as machine learning to create novel enzymes or variants.
- Identify new opportunities and expand capabilities. Initiate and lead product development in developing innovative technologies and products.
- Train and/or supervise junior level Team members.
- Ph.D. degree in Biochemistry, Molecular Biology, Enzymology or related field with 5+ years of relevant experience in protein development or MS with 5-10 year of Biotech industry experience.
- Proven track record of successful protein engineering and development projects.
- Expertise in protein expression systems (e.g., bacterial, yeast, mammalian).and proficiency in purification techniques including ion exchange and affinity chromatography, dialysis, filtration, electrophoresis, and protein characterization and analytical methods such as thermal shift assay.
- Broad experience and knowledge in molecular biology techniques including PCR, gene assembly and cloning; protein engineering methods such as mutagenesis, fusion protein construction, and variant library generation methods.
- In-depth knowledge of enzymes used in molecular biology, especially polymerases and ligases, and molecular biology methods for nucleic acid analysis.
- Working experience with AKTA FPLC systems and knowledge of protein structural biology is a plus.
- Able to work in a fast-paced and collaborative team environment.
- Excellent analytical thinking, problem solving, timeline management and interpersonal skills.
- Strong organizational skills, and solid communication skills including oral, written and presentation techniques.
The estimated base salary range for this position is $105,000 - $120,000. Compensation will be based on the candidate’s experience, skills, geographic location, and other job- related factors. In addition to base salary, we offer a total compensation package that includes a bonus plan and generous benefits.
At the heart of QIAGEN are our people who drive our success. We act with passion, always challenging the status quo to drive innovation and continuous improvement. We inspire with our leadership and make an impact with our actions. We create a collaborative, safe and engaging workplace which forms the basis for high performing individuals and teams. We drive accountability and entrepreneurial decision-making and want you to excel your growth and shape the future of QIAGEN.
QIAGEN is committed to creating a diverse environment and is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex (including pregnancy, childbirth, and medical conditions related to pregnancy, childbirth, or breastfeeding), sex stereotyping (including but not limited to assumptions about a person’s appearance or behavior, gender roles, gender expression, or gender identity), gender, gender identity, gender expression, national origin, age, mental or physical disability, ancestry, medical condition, marital status, military or veteran status, citizenship status, sexual orientation, genetic information, or any other status protected by applicable law.QIAGEN complies with applicable laws regarding the confidentiality of employee health information and the reasonable accommodation of individuals with disabilities and/or sincerely held religious beliefs. Candidates who require accommodation should contact [email protected] . This policy is part of QIAGEN’s ongoing efforts to support public health efforts and to ensure the safety and-well-being of its employees, customers, business partners, and community.
...Job Opening: Community Hospice Advocate - Consultant 1099 Job Description h/care, a dedicated leader in end-of-life care, is excited to announce a unique job opportunity for a passionate individual to join our team as a Community Hospice Advocate - Consultant 109...
...months or become permanent. This advertisement is for aCorrectional Officerposition located at CC#31in Redway, Humboldt County. Please... ...ability, as demonstrated by quality and breadth of experience, the following factors will provide the basis for competitively...
...and restroom facilitiesWashing, loading, and unloading towels for showersPerforming general repair/ maintenance of the storePicking up and taking all trash around travel centerProvide excellent guest service through well-maintained facilitiesQualificationsRequired QualificationsHighly...
...best in verification. You will be exposed to a diverse range of designs and application areas. We work on leading edge Audio,... ...REQUIREMENTS Key Qualifications ~ BSc/MSc in Electronic Engineering, Computer Engineering, or Computer Science. ~7 years of project...
We are looking for a dynamic and experienced Logistics Manager to oversee and manage the transportation, storage, and distribution of materials, equipment, and supplies essential for energy projects. In this role, you will help ensure efficient supply chain operations,...